What is a flexible manufacturing system and under what set of circumstances is it most appropriate quizlet?

1. Martin R. U.S. Outpatient Surgery Passes Inpatient, to 53 Million a Year. http://wwwtampabaycom/news/health/us-outpatient-surgery-passes-inpatient-to-53-million-a-year/1124313 Available at. Accessed 2010.

2. Weber DJ. Managing and preventing exposure events from inappropriately reprocessed endoscopes. Infect Control Hosp Epidemiol. 2012;33:657–660. [PubMed] [Google Scholar]

3. Uttley AH, Simpson RA. Audit of bronchoscope disinfection: a survey of procedures in England and Wales and incidents of mycobacterial contamination. J Hosp Infect. 1994;26:301–308. [PubMed] [Google Scholar]

4. Spach DH, Silverstein FE, Stamm WE. Transmission of infection by gastrointestinal endoscopy and bronchoscopy. Ann Intern Med. 1993;118:117–128. [PubMed] [Google Scholar]

5. Weber DJ, Rutala WA. Lessons from outbreaks associated with bronchoscopy. Infect Control Hosp Epidemiol. 2001;22:403–408. [PubMed] [Google Scholar]

6. Weber DJ, Rutala WA, DiMarino AJ., Jr . The prevention of infection following gastrointestinal endoscopy: the importance of prophylaxis and reprocessing. In: DiMarino AJ Jr, Benjamin SB, editors. Gastrointestinal Diseases: An Endoscopic Approach. 2nd ed. Slack Inc; Thorofare, NJ: 2002. pp. 87–106. [Google Scholar]

7. Meyers H, Brown-Elliott BA, Moore D. An outbreak of Mycobacterium chelonae infection following liposuction. Clin Infect Dis. 2002;34:1500–1507. [PubMed] [Google Scholar]

8. Lowry PW, Jarvis WR, Oberle AD. Mycobacterium chelonae causing otitis media in an ear-nose-and-throat practice. N Engl J Med. 1988;319:978–982. [PubMed] [Google Scholar]

9. Rutala WA, Weber DJ, Healthcare Infection Control Practices Advisory Committee Guideline for Disinfection and Sterilization in Healthcare Facilities. 2008. cdcgov/ncidod/dhqp/pdf/guidelines/Disinfection_Nov_2008pdf Available at.

10. Rutala WA, Weber DJ. Selection and use of disinfectants in healthcare. In: Mayhall CG, editor. Hospital Epidemiology and Infection Control. 4th ed. Wolters Kluwer/Lippincott Williams & Wilkins; Philadelphia: 2012. [Google Scholar]

11. Rutala WA, Weber DJ. Disinfection, sterilization, and control of hospital waste. In: Mandell GL, Bennett JE, Dolin R, editors. Principles and Practice of Infectious Diseases. 7th ed. Churchill Livingstone Elsevier; Philadelphia: 2009. pp. 3677–3695. [Google Scholar]

12. Rutala WA, Weber DJ. An overview of disinfection and sterilization. In: Rutala WA, editor. Disinfection, Sterilization and Antisepsis: Principles, Practices, Current Issues, New Research, and New Technologies. Association for Professionals in Infection Control and Epidemiology; Washington, DC: 2010. pp. 18–83. [PubMed] [Google Scholar]

13. Rutala WA, Weber DJ. Disinfection and sterilization in health-care facilities. In: Jarvis WR, editor. Bennett and Brachman's Hospital Infections. 6th ed. Wolters Kluwer/Lippincott Williams & Wilkins; Philadelphia: 2013. [Google Scholar]

14. Favero MS, Bond WW. Chemical disinfection of medical and surgical materials. In: Block SS, editor. Disinfection, Sterilization, and Preservation. 5th ed. Lippincott Williams & Wilkins; Philadelphia: 2001. pp. 881–917. [Google Scholar]

15. Spaulding EH. Chemical disinfection of medical and surgical materials. In: Lawrence C, Block SS, editors. Disinfection, Sterilization, and Preservation. Lea & Febiger; Philadelphia: 1968. pp. 517–531. [Google Scholar]

16. Simmons BP. CDC guidelines for the prevention and control of nosocomial infections: guideline for hospital environmental control. Am J Infect Control. 1983;11:97–120. [PubMed] [Google Scholar]

17. Block SS, editor. Disinfection, Sterilization, and Preservation. 5th ed. Lippincott Williams & Wilkins; Philadelphia: 2001. [Google Scholar]

18. Rutala WA, 1994, 1995, and 1996 APIC Guidelines Committee APIC guideline for selection and use of disinfectants. Association for Professionals in Infection Control and Epidemiology, Inc. Am J Infect Control. 1996;24:313–342. [PubMed] [Google Scholar]

19. Rutala WA. Disinfection, sterilization and waste disposal. In: Wenzel RP, editor. Prevention and Control of Nosocomial Infections. 3rd ed. Williams and Wilkins; Baltimore: 1997. pp. 539–593. [Google Scholar]

20. Garner JS, Favero MS. CDC guideline for handwashing and hospital environmental control, 1985. Infect Control. 1986;7:231–243. [PubMed] [Google Scholar]

21. Rutala WA. APIC guideline for selection and use of disinfectants. Am J Infect Control. 1990;18:99–117. [PubMed] [Google Scholar]

22. McDonnell G, Burke P. Disinfection: is it time to reconsider Spaulding? J Hosp Infect. 2011;78:163–170. [PubMed] [Google Scholar]

23. Miner N, Harris V, Cao TD. Aldahol high-level disinfectant. Am J Infect Control. 2010;38:205–211. [PubMed] [Google Scholar]

24. U.S. Food and Drug Administration FDA-Cleared Sterilant and High-Level Disinfectants with General Claims for Processing Reusable Medical and Dental Devices—March 2009. http://www.fda.gov/cdrh/ode/germlab.html Available at.

25. Alfa MJ, DeGagne P, Olson N. Comparison of ion plasma, vaporized hydrogen peroxide and 100% ethylene oxide sterilizers to the 12/88 ethylene oxide gas sterilizer. Infect Control Hosp Epidemiol. 1996;17:92–100. [PubMed] [Google Scholar]

26. Rutala WA, Weber DJ. New developments in reprocessing semicritical devices. Am J Infect Control. 2013;41(5 suppl):S60–S66. [PubMed] [Google Scholar]

27. Rutala WA, Gergen MF, Weber DJ. Disinfection of a probe used in ultrasound-guided prostate biopsy. Infect Control Hosp Epidemiol. 2007;28:916–919. [PubMed] [Google Scholar]

28. Rutala WA, Gergen MF, Weber DJ. Disinfection of an infrared coagulation device used to treat hemorrhoids. Am J Infect Control. 2012;40:78–79. [PubMed] [Google Scholar]

29. Wendelboe AM, Baumbach J, Blossom DB. Outbreak of cystoscopy related infections with Pseudomonas aeruginosa: New Mexico, 2007. J Urol. 2008;180:588–592. [PubMed] [Google Scholar]

30. Foliente RL, Kovacs BJ, Aprecio RM. Efficacy of high-level disinfectants for reprocessing gastrointestinal endoscopes in simulated-use testing. Gastrointest Endosc. 2001;53:456–462. [PubMed] [Google Scholar]

31. Kovacs BJ, Chen YK, Kettering JD. High-level disinfection of gastrointestinal endoscopes: are current guidelines adequate? Am J Gastroenterol. 1999;94:1546–1550. [PubMed] [Google Scholar]

32. Wallace RJ, Jr, Brown BA, Griffith DE. Nosocomial outbreaks/pseudo-outbreaks caused by nontuberculous mycobacteria. Annu Rev Microbiol. 1998;52:453–490. [PubMed] [Google Scholar]

33. Meenhorst PL, Reingold AL, Groothuis DG. Water-related nosocomial pneumonia caused by Legionella pneumophila serogroups 1 and 10. J Infect Dis. 1985;152:356–364. [PubMed] [Google Scholar]

34. Atlas RM. Legionella: from environmental habitats to disease pathology, detection and control. Environ Microbiol. 1999;1:283–293. [PubMed] [Google Scholar]

35. Rutala WA, Weber DJ. Water as a reservoir of nosocomial pathogens. Infect Control Hosp Epidemiol. 1997;18:609–616. [PubMed] [Google Scholar]

36. Weber DJ, Rutala WA. Environmental issues and nosocomial infections. In: Wenzel RP, editor. Prevention and Control of Nosocomial Infections. 3rd ed. Williams & Wilkins; Baltimore: 1997. pp. 491–514. [Google Scholar]

37. Petersen BT, Chennat J, Cohen J. Multisociety guideline on reprocessing flexible GI endoscopes: 2011. Infect Control Hosp Epidemiol. 2011;32:527–537. [PubMed] [Google Scholar]

38. Gerding DN, Peterson LR, Vennes JA. Cleaning and disinfection of fiberoptic endoscopes: evaluation of glutaraldehyde exposure time and forced-air drying. Gastroenterology. 1982;83:613–618. [PubMed] [Google Scholar]

39. Rutala WA, Clontz EP, Weber DJ. Disinfection practices for endoscopes and other semicritical items. Infect Control Hosp Epidemiol. 1991;12:282–288. [PubMed] [Google Scholar]

40. Centers for Disease Control and Prevention Guidelines for environmental infection control in health-care facilities, 2003. MMWR Recomm Rep. 2003;52(RR-10):1–44. [PubMed] [Google Scholar]

41. Huslage K, Rutala WA, Sickbert-Bennett E. A quantitative approach to defining high-touch surfaces in hospitals. Infect Control Hosp Epidemiol. 2010;31:850–853. [PubMed] [Google Scholar]

42. Sattar SA, Lloyd-Evans N, Springthorpe VS. Institutional outbreaks of rotavirus diarrhoea: potential role of fomites and environmental surfaces as vehicles for virus transmission. J Hyg. 1986;96:277–289. [PMC free article] [PubMed] [Google Scholar]

43. Weber DJ, Rutala WA. Role of environmental contamination in the transmission of vancomycin-resistant enterococci. Infect Control Hosp Epidemiol. 1997;18:306–309. [PubMed] [Google Scholar]

44. Ward RL, Bernstein DI, Knowlton DR. Prevention of surface-to-human transmission of rotaviruses by treatment with disinfectant spray. J Clin Microbiol. 1991;29:1991–1996. [PMC free article] [PubMed] [Google Scholar]

45. Sattar SA, Jacobsen H, Springthorpe VS. Chemical disinfection to interrupt transfer of rhinovirus type 14 from environmental surfaces to hands. Appl Environ Microbiol. 1993;59:1579–1585. [PMC free article] [PubMed] [Google Scholar]

46. Gwaltney JM, Jr, Hendley JO. Transmission of experimental rhinovirus infection by contaminated surfaces. Am J Epidemiol. 1982;116:828–833. [PubMed] [Google Scholar]

47. Sattar SA, Jacobsen H, Rahman H. Interruption of rotavirus spread through chemical disinfection. Infect Control Hosp Epidemiol. 1994;15:751–756. [PubMed] [Google Scholar]

48. Rutala WA, Barbee SL, Aguiar NC. Antimicrobial activity of home disinfectants and natural products against potential human pathogens. Infect Control Hosp Epidemiol. 2000;21:33–38. [PubMed] [Google Scholar]

49. Best M, Sattar SA, Springthorpe VS. Efficacies of selected disinfectants against Mycobacterium tuberculosis. J Clin Microbiol. 1990;28:2234–2239. [PMC free article] [PubMed] [Google Scholar]

50. Best M, Kennedy ME, Coates F. Efficacy of a variety of disinfectants against Listeria spp. Appl Environ Microbiol. 1990;56:377–380. [PMC free article] [PubMed] [Google Scholar]

51. Best M, Springthorpe VS, Sattar SA. Feasibility of a combined carrier test for disinfectants: studies with a mixture of five types of microorganisms. Am J Infect Control. 1994;22:152–162. [PubMed] [Google Scholar]

52. Springthorpe VS, Grenier JL, Lloyd-Evans N. Chemical disinfection of human rotaviruses: efficacy of commercially-available products in suspension tests. J Hyg. 1986;97:139–161. [PMC free article] [PubMed] [Google Scholar]

53. Sattar SA, Springthorpe VS. Survival and disinfectant inactivation of the human immunodeficiency virus: a critical review. Rev Infect Dis. 1991;13:430–447. [PubMed] [Google Scholar]

54. Weber DJ, Barbee SL, Sobsey MD. The effect of blood on the antiviral activity of sodium hypochlorite, a phenolic, and a quaternary ammonium compound. Infect Control Hosp Epidemiol. 1999;20:821–827. [PubMed] [Google Scholar]

55. Ciesek S, Friesland M, Steinmann J. How stable is the hepatitis C virus (HCV)? Environmental stability of HCV and its susceptibility to chemical biocides. J Infect Dis. 2010;201:1859–1866. [PubMed] [Google Scholar]

56. Dellanno C, Vega Q, Boesenberg D. The antiviral action of common household disinfectants and antiseptics against murine hepatitis virus, a potential surrogate for SARS coronavirus. Am J Infect Control. 2009;37:649–652. [PMC free article] [PubMed] [Google Scholar]

57. Jeong EK, Bae JE, Kim IS. Inactivation of influenza A virus H1N1 by disinfection process. Am J Infect Control. 2010;38:354–360. [PubMed] [Google Scholar]

58. Rutala WA, Gergen MF, Weber DJ. Efficacy of improved hydrogen peroxide against important healthcare-associated pathogens. Infect Control Hosp Epidemiol. 2012;33:1159–1161. [PubMed] [Google Scholar]

59. Pentella MA, Fisher T, Chandler S. Are disinfectants accurately prepared for use in hospital patient care areas? Infect Control Hosp Epidemiol. 2000;21:103. [Google Scholar]

60. Rutala WA, White MS, Gergen MF. Bacterial contamination of keyboards: efficacy and functional impact of disinfectants. Infect Control Hosp Epidemiol. 2006;27:372–377. [PubMed] [Google Scholar]

61. Rutala WA, Gergen MF, Weber DJ. Microbiologic evaluation of microfiber mops for surface disinfection. Am J Infect Control. 2007;35:569–573. [PubMed] [Google Scholar]

62. Westwood JC, Mitchell MA, Legace S. Hospital sanitation: the massive bacterial contamination of the wet mop. Appl Microbiol. 1971;21:693–697. [PMC free article] [PubMed] [Google Scholar]

63. Cooper RA, Griffith CJ, Malik RE. Monitoring the effectiveness of cleaning in four British hospitals. Am J Infect Control. 2007;35:338–341. [PubMed] [Google Scholar]

64. Boyce JM, Havill NL, Dumigan DG. Monitoring the effectiveness of hospital cleaning practices by use of an adenosine triphosphate bioluminescence assay. Infect Control Hosp Epidemiol. 2009;30:678–684. [PubMed] [Google Scholar]

65. Lewis T, Griffith C, Gallo M. A modified ATP benchmark for evaluating the cleaning of some hospital environmental surfaces. J Hosp Infect. 2008;69:156–163. [PubMed] [Google Scholar]

66. Carling PC, Parry MF, Rupp ME. Improving cleaning of the environment surrounding patients in 36 acute care hospitals. Infect Control Hosp Epidemiol. 2008;29:1035–1041. [PubMed] [Google Scholar]

67. Blue J, O’Neill C, Speziale P. Use of a fluorescent chemical as a quality indicator for a hospital cleaning program. Can J Infect Control. 2008;23:216–219. [PubMed] [Google Scholar]

68. U.S. Food and Drug Administration. Public Health Notification from FDA, CDC, EPA and OSHA: Avoiding Hazards with Using Cleaners and Disinfectants on Electronic Medical Equipment. U.S. Department of Health & Human Services, October 31, 2007.

69. Weber DJ, Rutala WA. Occupational risks associated with the use of selected disinfectants and sterilants. In: Rutala WA, editor. Disinfection, Sterilization, and Antisepsis in Healthcare. Polyscience Publications; Champlain, NY: 1998. pp. 211–226. [Google Scholar]

70. Spaulding EH. Alcohol as a surgical disinfectant. AORN J. 1964;2:67–71. [Google Scholar]

71. Morton HE. The relationship of concentration and germicidal efficiency of ethyl alcohol. Ann NY Acad Sci. 1950;53:191–196. [PubMed] [Google Scholar]

72. Ali Y, Dolan MJ, Fendler EJ. Alcohols. In: Block SS, editor. Disinfection, Sterilization, and Preservation. 5th ed. Lippincott Williams & Wilkins; Philadelphia: 2001. pp. 229–254. [Google Scholar]

73. Nye RN, Mallory TB. A note on the fallacy of using alcohol for the sterilization of surgical instruments. Boston Med Surg J. 1923;189:561–563. [Google Scholar]

74. Rutala WA, Peacock JE, Gergen MF. Efficacy of hospital germicides against adenovirus 8, a common cause of epidemic keratoconjunctivitis in health care facilities. Antimicrob Agents Chemother. 2006;50:1419–1424. [PMC free article] [PubMed] [Google Scholar]

75. Rutala WA, Weber DJ. Selection and use of disinfectants in healthcare. In: Mayhall CG, editor. Hospital Epidemiology and Infection Control. 3rd ed. Lippincott Williams & Wilkins; Philadelphia: 2004. pp. 1473–1522. [Google Scholar]

76. Rutala WA, Weber DJ. Uses of inorganic hypochlorite (bleach) in health-care facilities. Clin Microbiol Rev. 1997;10:597–610. [PMC free article] [PubMed] [Google Scholar]

77. Merritt K, Hitchins VM, Brown SA. Safety and cleaning of medical materials and devices. J Biomed Mater Res. 2000;53:131–136. [PubMed] [Google Scholar]

78. Jakobsson SW, Rajs J, Jonsson JA. Poisoning with sodium hypochlorite solution: report of a fatal case, supplemented with an experimental and clinico-epidemiological study. Am J Forens Med Pathol. 1991;12:320–327. [PubMed] [Google Scholar]

79. Heidemann SM, Goetting MG. Treatment of acute hypoxemic respiratory failure caused by chlorine exposure. Pediatr Emerg Care. 1991;7:87–88. [PubMed] [Google Scholar]

80. French RJ, Tabb HG, Rutledge LJ. Esophageal stenosis produced by ingestion of bleach: report of two cases. South Med J. 1970;63:1140–1144. [PubMed] [Google Scholar]

81. Ingram TA. Response of the human eye to accidental exposure to sodium hypochlorite. J Endod. 1990;16:235–238. [PubMed] [Google Scholar]

82. Mrvos R, Dean BS, Krenzelok EP. Home exposures to chlorine/chloramine gas: review of 216 cases. South Med J. 1993;86:654–657. [PubMed] [Google Scholar]

83. Rutala WA, Cole EC, Thomann CA. Stability and bactericidal activity of chlorine solutions. Infect Control Hosp Epidemiol. 1998;19:323–327. [PubMed] [Google Scholar]

84. Sampson MN, Muir AVG. Not all super-oxidized waters are the same. J Hosp Infect. 2002;52:227–228. [PubMed] [Google Scholar]

85. Selkon JB, Babb JR, Morris R. Evaluation of the antimicrobial activity of a new super-oxidized water, Sterilox®, for the disinfection of endoscopes. J Hosp Infect. 1999;41:59–70. [PubMed] [Google Scholar]

86. Shetty N, Srinivasan S, Holton J. Evaluation of microbicidal activity of a new disinfectant: Sterilox® 2500 against Clostridium difficile spores, Helicobacter pylori, vancomycin resistant Enterococcus species, Candida albicans and several Mycobacterium species. J Hosp Infect. 1999;41:101–105. [PubMed] [Google Scholar]

87. Nagington J, Sutehall GM, Whipp P. Tonometer disinfection and viruses. Br J Ophthalmol. 1983;67:674–676. [PMC free article] [PubMed] [Google Scholar]

88. Centers for Disease Control Acquired immune deficiency syndrome (AIDS): precautions for clinical and laboratory staffs. MMWR Morb Mortal Wkly Rep. 1982;31:577–580. [PubMed] [Google Scholar]

89. Centers for Disease Control Recommendations for prevention of HIV transmission in health-care settings. MMWR Morb Mortal Wkly Rep. 1987;36:S3–S18. [Google Scholar]

90. Centers for Disease Control Guidelines for prevention of transmission of human immunodeficiency virus and hepatitis B virus to health-care and public-safety workers. MMWR Morb Mortal Wkly Rep. 1989;38(S-6):1–37. [PubMed] [Google Scholar]

91. Garner JS, Simmons BP. Guideline for isolation precautions in hospitals. Infect Control. 1983;4(4 suppl):245–325. [PubMed] [Google Scholar]

92. Bloomfield SF, Miller EA. A comparison of hypochlorite and phenolic disinfectants for disinfection of clean and soiled surfaces and blood spillages. J Hosp Infect. 1989;13:231–239. [PubMed] [Google Scholar]

93. Rutala WA, Weber DJ. Disinfection of endoscopes: review of new chemical sterilants used for high-level disinfection. Infect Control Hosp Epidemiol. 1999;20:69–76. [PubMed] [Google Scholar]

94. Gerding DN, Muto CA, Owens RC., Jr Measures to control and prevent Clostridium difficile infection. Clin Infect Dis. 2008;46(suppl 1):S43–S49. [PubMed] [Google Scholar]

95. Perez J, Springthorpe S, Sattar SA. Activity of selected oxidizing microbicides against spores of Clostridium difficile: relevance to environmental control. Am J Infect Control. 2005;33:320–325. [PubMed] [Google Scholar]

96. Orenstein R, Aronhalt KC, McManus JE., Jr A targeted strategy to wipe out Clostridium difficile. Infect Control Hosp Epidemiol. 2011;32:1137–1139. [PubMed] [Google Scholar]

97. Hacek DM, Ogle AM, Fisher A. Significant impact of terminal room cleaning with bleach on reducing nosocomial Clostridium difficile. Am J Infect Control. 2010;38:350–353. [PubMed] [Google Scholar]

98. Mayfield JL, Leet T, Miller J. Environmental control to reduce transmission of Clostridium difficile. Clin Infect Dis. 2000;31:995–1000. [PubMed] [Google Scholar]

99. Helms CM, Massanari RM, Zeitler R. Legionnaires’ disease associated with a hospital water system: a cluster of 24 nosocomial cases. Ann Intern Med. 1983;99:172–178. [PubMed] [Google Scholar]

100. Helms C, Massanari R, Wenzel R. Legionnaires’ disease associated with a hospital water system. A five-year progress report on continuous hyperchlorination. JAMA. 1988;259:2423–2427. [PubMed] [Google Scholar]

101. Cheung RJ, Ortiz D, DiMarino AJ., Jr GI endoscopic reprocessing practices in the United States. Gastrointest Endosc. 1999;50:362–368. [PubMed] [Google Scholar]

102. Miner NA, McDowell JW, Willcockson GW. Antimicrobial and other properties of a new stabilized alkaline glutaraldehyde disinfectant/sterilizer. Am J Hosp Pharm. 1977;34:376–382. [PubMed] [Google Scholar]

103. Pepper RE. Comparison of the activities and stabilities of alkaline glutaraldehyde sterilizing solutions. Infect Control. 1980;1:90–92. [PubMed] [Google Scholar]

104. Scott EM, Gorman SP. Glutaraldehyde. In: Block SS, editor. Disinfection, Sterilization, and Preservation. 5th ed. Lippincott Williams & Wilkins; Philadelphia: 2001. pp. 361–381. [Google Scholar]

105. Rutala WA, Gergen MF, Weber DJ. Inactivation of Clostridium difficile spores by disinfectants. Infect Control Hosp Epidemiol. 1993;14:36–39. [PubMed] [Google Scholar]

106. Dyas A, Das BC. The activity of glutaraldehyde against Clostridium difficile. J Hosp Infect. 1985;6:41–45. [PubMed] [Google Scholar]

107. van Klingeren B, Pullen W. Glutaraldehyde resistant mycobacteria from endoscope washers. J Hosp Infect. 1993;25:147–149. [PubMed] [Google Scholar]

108. Griffiths PA, Babb JR, Bradley CR. Glutaraldehyde-resistant Mycobacterium chelonae from endoscope washer disinfectors. J Appl Microbiol. 1997;82:519–526. [PubMed] [Google Scholar]

109. Fisher CW, Fiorello A, Shaffer D. Aldehyde-resistant mycobacteria bacteria associated with the use of endoscope reprocessing systems. Am J Infect Control. 2012;40:880–882. [PMC free article] [PubMed] [Google Scholar]

110. Webster E, Ribner B, Streed LL. Microbial contamination of activated 2% glutaraldehyde used in high-level disinfection of endoscopes [abstract] Am J Infect Control. 1996;24:153. [Google Scholar]

111. Barbee SL, Weber DJ, Sobsey MD, Rutala WA. Inactivation of Cryptosporidium parvum oocyst infectivity by disinfection and sterilization processes. Gastrointest Endosc. 1999;49:605–611. [PubMed] [Google Scholar]

112. Laskowski LF, Marr JJ, Spernoga JF. Fastidious mycobacteria grown from porcine prosthetic-heart-valve cultures. N Engl J Med. 1977;297:101–102. [PubMed] [Google Scholar]

113. Lorena NS, Duarte RS, Pitombo MB. Vol. 36. 2009. Rapidly growing mycobacteria infection after videosurgical procedures-the glutaraldehyde hypothesis; pp. 266–267. (Rev Col Bras Cir). [PubMed] [Google Scholar]

114. Svetlikova Z, Skovierova H, Niederweis M. Role of porins in the susceptibility of Mycobacterium smegmatis and Mycobacterium chelonae to aldehyde-based disinfectants and drugs. Antimicrob Agents Chemother. 2009;53:4015–4018. [PMC free article] [PubMed] [Google Scholar]

115. Mbithi JN, Springthorpe VS, Sattar SA. Bactericidal, virucidal, and mycobactericidal activities of reused alkaline glutaraldehyde in an endoscopy unit. J Clin Microbiol. 1993;31:2988–2995. [PMC free article] [PubMed] [Google Scholar]

116. Cole EC, Rutala WA, Nessen L. Effect of methodology, dilution, and exposure time on the tuberculocidal activity of glutaraldehyde-based disinfectants. Appl Environ Microbiol. 1990;56:1813–1817. [PMC free article] [PubMed] [Google Scholar]

117. Collins FM, Montalbine V. Mycobactericidal activity of glutaraldehyde solutions. J Clin Microbiol. 1976;4:408–412. [PMC free article] [PubMed] [Google Scholar]

118. Overton D, Burgess JO, Beck B. Glutaraldehyde test kits: evaluation for accuracy and range. Gen Dent. 1989;37:126. [PubMed] [Google Scholar]

119. Cooke RPD, Goddard SV, Chatterley R. Monitoring glutaraldehyde dilution in automated washer/disinfectors. J Hosp Infect. 2001;48:242–246. [PubMed] [Google Scholar]

120. Farina A, Fievet MH, Plassart F. Residual glutaraldehyde levels in fiberoptic endoscopes: measurement and implications for patient toxicity. J Hosp Infect. 1999;43:293–297. [PubMed] [Google Scholar]

121. Dailey JR, Parnes RE, Aminlari A. Glutaraldehyde keratopathy. Am J Ophthalmol. 1993;115:256–258. [PubMed] [Google Scholar]

122. Newman MA, Kachuba JB. Glutaraldehyde: a potential health risk to nurses. Gastroenterol Nurs. 1992;14:296–300. [PubMed] [Google Scholar]

123. Turner FJ. Hydrogen peroxide and other oxidant disinfectants. In: Block SS, editor. Disinfection, Sterilization, and Preservation. 3rd ed. Lea & Febiger; Philadelphia: 1983. pp. 240–250. [Google Scholar]

124. Block SS. Peroxygen compounds. In: Block SS, editor. Disinfection, Sterilization, and Preservation. 5th ed. Lippincott Williams & Wilkins; Philadelphia: 2001. pp. 185–204. [Google Scholar]

125. Sattar SA, Springthorpe VS, Rochon M. A product based on accelerated and stabilized hydrogen peroxide: evidence for broad-spectrum germicidal activity. Can J Infect Control. 1998;(Winter):123–130. [Google Scholar]

126. Rutala WA, Gergen MF, Weber DJ. Sporicidal activity of chemical sterilants used in hospitals. Infect Control Hosp Epidemiol. 1993;14:713–718. [PubMed] [Google Scholar]

127. Maillard J-Y. Innate resistance to sporicides and potential failure to decontaminate. J Hosp Infect. 2011;77:204–209. [PubMed] [Google Scholar]

128. Silvany RE, Dougherty JM, McCulley JP. The effect of currently available contact lens disinfection systems on Acanthamoeba castellanii and Acanthamoeba polyphaga. Ophthalmology. 1990;97:286–290. [PubMed] [Google Scholar]

129. Neely AN, Maley MP. The 1999 Lindberg award. 3% hydrogen peroxide for the gram-positive disinfection of fabrics. J Burn Care Rehabil. 1999;20:471–477. [PubMed] [Google Scholar]

130. Vesley D, Norlien KG, Nelson B. Significant factors in the disinfection and sterilization of flexible endoscopes. Am J Infect Control. 1992;20:291–300. [PubMed] [Google Scholar]

131. Levenson JE. Corneal damage from improperly cleaned tonometer tips. Arch Ophthalmol. 1989;107:1117. [PubMed] [Google Scholar]

132. Omidbakhsh N, Sattar SA. Broad-spectrum microbicidal activity, toxicologic assessment, and materials compatibility of a new generation of accelerated hydrogen peroxide-based environmental surface disinfectant. Am J Infect Control. 2006;34:251–257. [PMC free article] [PubMed] [Google Scholar]

133. Sattar SA, Adegbunrin O, Ramirez J. Combined application of simulated reuse and quantitative carrier test to assess high-level disinfection: experiments with an accelerated hydrogen peroxide-based formulation. Am J Infect Control. 2002;30:449–457. [PubMed] [Google Scholar]

134. Omidbakhsh N. A new peroxide-based flexible endoscope-compatible high-level disinfectant. Am J Infect Control. 2006;34:571–577. [PubMed] [Google Scholar]

135. Omidbakhsh N, Kenny N. An accelerated hydrogen peroxide (AHP)-based fast-acting and reusable microbicide for manual disinfection of heat sensitive semi-critical medical devices. Can J Infect Control. 2008;23:81–88. [PubMed] [Google Scholar]

136. Rochon M, Sullivan N. Products based on accelerated and stabilized hydrogen peroxide: evidence for cleaning and sanitizing efficiency, environmental and human safety and non-corrosiveness. Can J Infect Control. 1999;(Summer):51–55. [Google Scholar]

137. Gottardi W. Iodine and iodine compounds. In: Block SS, editor. Disinfection, Sterilization, and Preservation. 5th ed. Lippincott Williams & Wilkins; Philadelphia: 2001. pp. 159–184. [Google Scholar]

138. Craven DE, Moody B, Connolly MG. Pseudobacteremia caused by povidone-iodine solution contaminated with Pseudomonas cepacia. N Engl J Med. 1981;305:621–623. [PubMed] [Google Scholar]

139. Berkelman RL, Lewin S, Allen JR. Pseudobacteremia attributed to contamination of povidone-iodine with Pseudomonas cepacia. Ann Intern Med. 1981;95:32–36. [PubMed] [Google Scholar]

140. Weber DJ, Rutala WA, Sickbert-Bennett EE. Outbreaks associated with contaminated antiseptics and disinfectants. Antimicrob Agents Chemother. 2007;51:916–919. [PMC free article] [PubMed] [Google Scholar]

141. Rutala WA, Cole EC, Wannamaker NS. Inactivation of Mycobacterium tuberculosis and Mycobacterium bovis by 14 hospital disinfectants. Am J Med. 1991;91:267S–271S. [PubMed] [Google Scholar]

142. Klein M, DeForest A. Vol. 49. 1963. The inactivation of viruses by ger­micides; pp. 116–118. (Chem Specialists Manuf Assoc Proc). [Google Scholar]

143. Berkelman RL, Holland BW, Anderson RL. Increased bactericidal activity of dilute preparations of povidone-iodine solutions. J Clin Microbiol. 1982;15:635–639. [PMC free article] [PubMed] [Google Scholar]

144. Wallbank AM, Drulak M, Poffenroth L. Wescodyne: lack of activity against poliovirus in the presence of organic matter. Health Lab Sci. 1978;15:133–137. [PubMed] [Google Scholar]

145. Favero MS, Bond WW. Chemical disinfection of medical and surgical materials. In: Block SS, editor. Disinfection, Sterilization, and Preservation. 4th ed. Lea & Febiger; Philadelphia: 1991. pp. 617–641. [Google Scholar]

146. Medcom Frequently Asked Questions www.medcompnet.com/faq/faq/html Available at. Accessed June 2000.

147. Gordon MD, Ezzell RJ, Bruckner NI. Enhancement of mycobactericidal activity of glutaraldehyde with α,β-unsaturated and aromatic aldehydes. J Indus Microbiol. 1994;13:77–82. [Google Scholar]

148. Rutala WA, Weber DJ. New disinfection and sterilization methods. Emerg Infect Dis. 2001;7:348–353. [PMC free article] [PubMed] [Google Scholar]

149. Gregory AW, Schaalje GB, Smart JD. The mycobactericidal efficacy of ortho-phthalaldehyde and the comparative resistances of Mycobacterium bovis, Mycobacterium terrae, and Mycobacterium chelonae. Infect Control Hosp Epidemiol. 1999;20:324–330. [PubMed] [Google Scholar]

150. Walsh SE, Maillard JY, Russell AD. Ortho-phthalaldehyde: a possible alternative to glutaraldehyde for high level disinfection. J Appl Microbiol. 1999;86:1039–1046. [PubMed] [Google Scholar]

151. Alfa MJ, Sitter DL. In-hospital evaluation of ortho-phthalaldehyde as a high level disinfectant for flexible endoscopes. J Hosp Infect. 1994;26:15–26. [PMC free article] [PubMed] [Google Scholar]

152. Roberts CG, Chan-Myers HB, Favero MS. Virucidal activity of ortho-phthalaldehyde solutions against hepatitis B and C viruses. Am J Infect Control. 2008;36:223–226. [PubMed] [Google Scholar]

153. Sokol WN. Nine episodes of anaphylaxis following cystoscopy caused by Cidex OPA (ortho-phthalaldehyde) high-level disinfectant in 4 patients after cystoscopy. J Allergy Clin Immunol. 2004;114:392–397. [PubMed] [Google Scholar]

154. Miyajima K, Yoshida J, Kumagai S. Ortho-phthalaldehyde exposure levels among endoscope disinfection workers. Sangyo Eiseigaku Zasshi. 2010;52:74. [PubMed] [Google Scholar]

155. Tucker RC, Lestini BJ, Marchant RE. Surface analysis of clinically used expanded PTFE endoscopic tubing treated by the STERIS PROCESS. ASAIO J. 1996;42:306–313. [PubMed] [Google Scholar]

156. U.S. Food and Drug Administration Steris System 1E Liquid Chemical Sterilant. 2012. http://wwwfdagov/MedicalDevices/ProductsandMedicalProcedures/DeviceApprovalsandClearances/Recently-ApprovedDevices/ucm207489htm Available at.

157. Malchesky PS. Medical applications of peracetic acid. In: Block SS, editor. Disinfection, Sterilization, and Preservation. 5th ed. Lippincott Williams & Wilkins; Philadelphia: 2001. pp. 979–996. [Google Scholar]

158. Mannion PT. The use of peracetic acid for the reprocessing of flexible endoscopes and rigid cystoscopes and laparoscopes. J Hosp Infect. 1995;29:313–315. [PubMed] [Google Scholar]

159. Bradley CR, Babb JR, Ayliffe GA. Evaluation of the Steris System 1 Peracetic Acid Endoscope Processor. J Hosp Infect. 1995;29:143–151. [PubMed] [Google Scholar]

160. Duc DL, Ribiollet A, Dode X. Evaluation of the microbicidal efficacy of Steris System 1 for digestive endoscopes using GERMANDE and ASTM validation protocols. J Hosp Infect. 2001;48:135–141. [PubMed] [Google Scholar]

161. Alfa MJ, Olson N, Degagne P. New low temperature sterilization technologies: microbicidal activity and clinical efficacy. In: Rutala WA, editor. Disinfection, Sterilization, and Antisepsis in Healthcare. Polyscience Publications; Champlain, NY: 1998. pp. 67–78. [Google Scholar]

162. Alfa MJ, DeGagne P, Olson N. Comparison of liquid chemical sterilization with peracetic acid and ethylene oxide sterilization for long narrow lumens. Am J Infect Control. 1998;26:469–477. [PubMed] [Google Scholar]

163. Fuselier HA, Jr, Mason C. Liquid sterilization versus high level disinfection in the urologic office. Urology. 1997;50:337–340. [PubMed] [Google Scholar]

164. Seballos RJ, Walsh AL, Mehta AC. Clinical evaluation of a liquid chemical sterilization system for flexible bronchoscopes. J Bronch. 1995;2:192–199. [Google Scholar]

165. Wallace CG, Agee PM, Demicco DD. Liquid chemical sterilization using peracetic acid: an alternative approach to endoscope processing. ASAIO J. 1995;41:151–154. [PubMed] [Google Scholar]

166. Centers for Disease Control and Prevention Bronchoscopy-related infections and pseudoinfections—New York, 1996 and 1998. MMWR Morb Mortal Wkly Rep. 1999;48:557–560. [PubMed] [Google Scholar]

167. U.S. Food and Drug Administration, Centers for Disease Control and Prevention . U.S. Food and Drug Administration; Rockville, MD: 1999. FDA and CDC Public Health Advisory: Infections from Endoscopes Inadequately Reprocessed by an Automated Endoscope Reprocessing System. [Google Scholar]

168. Middleton AM, Chadwick MV, Gaya H. Disinfection of bronchoscopes, contaminated in vitro with Mycobacterium tuberculosis, Mycobacterium avium-intracellulare and Mycobacterium chelonae in sputum, using stabilized, buffered peracetic acid solution (‘Nu-Cidex. J Hosp Infect. 1997;37:137–143. [PubMed] [Google Scholar]

169. Holton J, Shetty N. In-use stability of Nu-Cidex. J Hosp Infect. 1997;35:245–248. [PubMed] [Google Scholar]

170. Alasri A, Roques C, Michel G. Bactericidal properties of peracetic acid and hydrogen peroxide, alone and in combination, and chlorine and formaldehyde against bacterial water strains. Can J Microbiol. 1992;38:635–642. [PubMed] [Google Scholar]

171. Stanley P. Destruction of a glutaraldehyde-resistant mycobacterium by a per-oxygen disinfectant [abstract] Am J Infect Control. 1998;26:185. [Google Scholar]

172. Fleming SJ, Foreman K, Shanley K. Dialyser reprocessing with Renalin. Am J Nephrol. 1991;11:27–31. [PubMed] [Google Scholar]

173. Finelli L, Miller JT, Tokars JI. National surveillance of dialysis-associated diseases in the United States, 2002. Semin Dial. 2005;18:52–61. [PubMed] [Google Scholar]

174. Rutala WA, Cole EC. Ineffectiveness of hospital disinfectants against bacteria: a collaborative study. Infect Control. 1987;8:501–506. [PubMed] [Google Scholar]

175. Prindle RF. Phenolic compounds. In: Block SS, editor. Disinfection, Sterilization, and Preservation. 3rd ed. Lea & Febiger; Philadelphia: 1983. pp. 197–224. [Google Scholar]

176. Cole EC, Rutala WA, Samsa GP. Disinfectant testing using a modified use-dilution method: collaborative study. J Assoc Off Anal Chem. 1988;71:1187–1194. [PubMed] [Google Scholar]

177. Goddard PA, McCue KA. Phenolic compounds. In: Block SS, editor. Disinfection, Sterilization, and Preservation. 5th ed. Lippincott Williams & Wilkins; Philadelphia: 2001. pp. 255–281. [Google Scholar]

178. Sagripanti JL, Eklund CA, Trost PA. Comparative sensitivity of 13 species of pathogenic bacteria to seven chemical germicides. Am J Infect Control. 1997;25:335–339. [PubMed] [Google Scholar]

179. Wysowski DK, Flynt JW, Jr, Goldfield M. Epidemic neonatal hyperbilirubinemia and use of a phenolic disinfectant detergent. Pediatrics. 1978;61:165–170. [PubMed] [Google Scholar]

180. Doan HM, Keith L, Shennan AT. Phenol and neonatal jaundice. Pediatrics. 1979;64:324–325. [PubMed] [Google Scholar]

181. Shickman MD, Guze LB, Pearce ML. Bacteremia following cardiac catheterization. N Engl J Med. 1959;260:1164–1166. [PubMed] [Google Scholar]

182. Ehrenkranz NJ, Bolyard EA, Wiener M. Antibiotic-sensitive Serratia marcescens infections complicating cardiopulmonary operations: contaminated disinfectant as a reservoir. Lancet. 1980;2:1289–1292. [PubMed] [Google Scholar]

183. Mbithi JN, Springthorpe VS, Sattar SA. Chemical disinfection of hepatitis A virus on environmental surfaces. Appl Environ Microbiol. 1990;56:3601–3604. [PMC free article] [PubMed] [Google Scholar]

184. Petrocci AN. Surface active agents: quaternary ammonium compounds. In: Block SS, editor. Disinfection, Sterilization, and Preservation. 3rd ed. Lea & Febiger; Philadelphia: 1983. pp. 309–329. [Google Scholar]

185. Doultree JC, Druce JD, Birch CJ. Inactivation of feline calicivirus, a Norwalk virus surrogate. J Hosp Infect. 1999;41:51–57. [PubMed] [Google Scholar]

186. Cefai C, Richards J, Gould FK. An outbreak of respiratory tract infection resulting from incomplete disinfection of ventilatory equipment. J Hosp Infect. 1990;15:177–182. [PubMed] [Google Scholar]

187. Gurevich I, Tafuro P, Ristuccia P. Disinfection of respirator tubing: a comparison of chemical versus hot water machine-assisted processing. J Hosp Infect. 1983;4:199–208. [PubMed] [Google Scholar]

188. Rutala WA, Weber DJ, Gergen MF. Efficacy of a washer-pasteurizer for disinfection of respiratory-care equipment. Infect Control Hosp Epidemiol. 2000;21:333–336. [PubMed] [Google Scholar]

189. Jette LP, Lambert NG. Evaluation of two hot water washer disinfectors for medical instruments. Infect Control Hosp Epidemiol. 1988;9:194–199. [PubMed] [Google Scholar]

190. Bak J, Ladefoged SD, Tvede M. Dose requirements for UVC disinfection of catheter biofilms. Biofouling. 2009;25:289–296. [PubMed] [Google Scholar]

191. Kac G, Gueneret M, Rodi A. Evaluation of a new disinfection procedure for ultrasound probes using ultraviolet light. J Hosp Infect. 2007;65:163–168. [PubMed] [Google Scholar]

192. Rastogi VK, Wallace L, Smith LS. Disinfection of Acinetobacter baumannii–contaminated surfaces relevant to medical treatment facilities with ultraviolet C light. Mil Med. 2007;172:1166–1169. [PubMed] [Google Scholar]

193. Nerandzic MM, Cadnum JL, Eckart KE. Evaluation of a hand-held far-ultraviolet radiation device for decontamination of Clostridium difficile and other healthcare-associated pathogens. BMC Infect Dis. 2012;12:120. [PMC free article] [PubMed] [Google Scholar]

194. Association for the Advancement of Medical Instrumentation, American National Standards Institute . Association for the Advancement of Medical Instrumentation; Arlington, VA: 2010. Comprehensive Guide to Steam Sterilization and Sterility Assurance in Health Care Facilities. [Google Scholar]

195. Singh J, Bhatia R, Gandhi JC. Outbreak of viral hepatitis B in a rural community in India linked to inadequately sterilized needles and syringes. Bull World Health Organ. 1998;76:93–98. [PMC free article] [PubMed] [Google Scholar]

196. Eickhoff TC. An outbreak of surgical wound infections due to Clostridium perfringens. Surg Gynecol Obstet. 1962;114:102–108. [PubMed] [Google Scholar]

197. Tosh PK, Disbot M, Duffy JM. Outbreak of Pseudomonas aeruginosa surgical site infections after arthroscopic procedures: Texas, 2009. Infect Control Hosp Epidemiol. 2011;32:1179–1186. [PubMed] [Google Scholar]

198. Favero MS. Sterility assurance: concepts for patient safety. In: Rutala WA, editor. Disinfection, Sterilization and Antisepsis: Principles and Practices in Healthcare Facilities. Association for Professional in Infection Control and Epidemiology; Washington, DC: 2001. pp. 110–119. [Google Scholar]

199. Oxborrow GS, Berube R. Sterility testing-validation of sterilization processes, and sporicide testing. In: Block SS, editor. Disinfection, Sterilization, and Preservation. 4th ed. Lea & Febiger; Philadelphia: 1991. pp. 1047–1057. [Google Scholar]

200. Rutala WA, Weber DJ. Clinical effectiveness of low-temperature sterilization technologies. Infect Control Hosp Epidemiol. 1998;19:798–804. [PubMed] [Google Scholar]

201. Adler S, Scherrer M, Daschner FD. Costs of low-temperature plasma sterilization compared with other sterilization methods. J Hosp Infect. 1998;40:125–134. [PubMed] [Google Scholar]

202. Joslyn L. Sterilization by heat. In: Block SS, editor. Disinfection, Sterilization, and Preservation. 5th ed. Lippincott Williams & Wilkins; Philadelphia: 2001. pp. 695–728. [Google Scholar]

203. Silverstone SE, Hill DE. Evaluation of sterilization of dental handpieces by heating in synthetic compressor lubricant. Gen Dent. 1999;47:158–160. [PubMed] [Google Scholar]

204. Bucx MJ, Veldman DJ, Beenhakker MM. The effect of steam sterilization at 134 degrees C on light intensity provided by fibrelight Macintoch laryngoscopes. Anaesthesia. 2000;55:185–186. [PubMed] [Google Scholar]

205. Gilbert JA, Phillips HO. The effect of steam sterilization on plaster casting material. Clin Orthop Relat Res. 1984;(190):241–244. [PubMed] [Google Scholar]

206. Bryce EA, Roberts FJ, Clements B. When the biological indicator is positive: investigating autoclave failures. Infect Control Hosp Epidemiol. 1997;18:654–656. [PubMed] [Google Scholar]

207. Rutala WA, Stiegel MM, Sarubbi FA., Jr Decontamination of laboratory microbiological waste by steam sterilization. Appl Environ Microbiol. 1982;43:1311–1316. [PMC free article] [PubMed] [Google Scholar]

208. Rutala WA. Disinfection and flash sterilization in the operating room. J Ophthalm Nurs Technol. 1991;10:106–115. [PubMed] [Google Scholar]

209. Seavey R. Immediate use steam sterilization: moving beyond current policy. Am J Infect Control. 2013;41(5 suppl):S46–S48. [PubMed] [Google Scholar]

210. Association for the Advancement of Medical Instrumentation, Accreditation Association for Ambulatory Health Care, Association of Perioperative Registered Nurses Immediate-Use Steam Sterilization. http://www.aami.org/publications/standards/ST79_Immediate_Use_Statement.pdf Available at.

211. Ernst RR, Doyle JE. Sterilization with gaseous ethylene oxide: a review of chemical and physical factors. Biotech Bioeng. 1968;10:1–31. [Google Scholar]

212. Joslyn L. Gaseous chemical sterilization. In: Block SS, editor. Disinfection, Sterilization, and Preservation. 5th ed. Lippincott Williams & Wilkins; Philadelphia: 2001. pp. 337–360. [Google Scholar]

213. Association for the Advancement of Medical Instrumentation . AAMI; Arlington, VA: 1999. Ethylene Oxide Sterilization in Health Care Facilities: Safety and Effectiveness. Report No. ANSI/AAMI ST41. [Google Scholar]

214. Association for the Advancement of Medical Instrumentation . AAMI; Arlington, VA: 2008. Ethylene Oxide Sterilization in Health Care Facilities: Safety and Effectiveness. Report No. ANSI/AAMI ST41. [Google Scholar]

215. U. S. Department of Health and Human Services. National Toxicology Program http://ntp-server.niehs.nih.gov/ Available at.

216. Ethylene oxide sterilization: how hospitals can adapt to the changes. Health Devices. 1994;23:485–492. [PubMed] [Google Scholar]

217. Ries MD, Weaver K, Beals N. Safety and efficacy of ethylene oxide sterilized polyethylene in total knee arthroplasty. Clin Orthop Relat Res. 1996;(331):159–163. [PubMed] [Google Scholar]

218. Alfa MJ, DeGagne P, Olson N. Bacterial killing ability of 10% ethylene oxide plus 90% hydrochlorofluorocarbon sterilizing gas. Infect Control Hosp Epidemiol. 1997;18:641–645. [PubMed] [Google Scholar]

219. Rutala WA, Gergen MF, Weber DJ. Comparative evaluation of the sporicidal activity of new low-temperature sterilization technologies: ethylene oxide, 2 plasma sterilization systems, and liquid peracetic acid. Am J Infect Control. 1998;26:393–398. [PubMed] [Google Scholar]

220. Parisi AN, Young WE. Sterilization with ethylene oxide and other gases. In: Block SS, editor. Disinfection, Sterilization, and Preservation. 4th ed. Lea & Febiger; Philadelphia: 1991. pp. 580–595. [Google Scholar]

221. Holler C, Martiny H, Christiansen B. The efficacy of low temperature plasma (LTP) sterilization, a new sterilization technique. Zentralbl Hyg Umweltmed. 1993;194:380–391. [PubMed] [Google Scholar]

222. Parker HH, Johnson RB. Effectiveness of ethylene oxide for sterilization of dental handpieces. J Dent. 1995;23:113–115. [PubMed] [Google Scholar]

223. Borneff M, Ruppert J, Okpara J. Efficacy testing of low-temperature plasma sterilization (LTP) with test object models simulating practice conditions. Zentralbl Steril. 1995;3:361–371. [Google Scholar]

224. Borneff-Lipp M, Okpara J, Bodendorf M. Validation of low-temperature-plasma (LPT) sterilization systems: comparison of two technical versions, the Sterrad 100, 1.8 and the 100S. Hyg Mikrobiol. 1997;3:21–28. [Google Scholar]

225. Jacobs PT, Lin SM. Sterilization processes utilizing low-temperature plasma. In: Block SS, editor. Disinfection, Sterilization, and Preservation. 5th ed. Lippincott Williams & Wilkins; Philadelphia: 2001. pp. 747–763. [Google Scholar]

226. Rutala WA, Gergen MF, Weber DJ. Sporicidal activity of a new low-temperature sterilization technology: the Sterrad 50 sterilizer. Infect Control Hosp Epidemiol. 1999;20:514–516. [PubMed] [Google Scholar]

227. Roberts C, Antonoplos P. Inactivation of human immunodeficiency virus type 1, hepatitis A virus, respiratory syncytial virus, vaccinia virus, herpes simplex virus type 1, and poliovirus type 2 by hydrogen peroxide gas plasma sterilization. Am J Infect Control. 1998;26:94–101. [PubMed] [Google Scholar]

228. Kyi MS, Holton J, Ridgway GL. Assessment of the efficacy of a low temperature hydrogen peroxide gas plasma sterilization system. J Hosp Infect. 1995;31:275–284. [PubMed] [Google Scholar]

229. Borneff-Lipp M, Kaetzke A, Durr M. Evaluation of low temperature hydrogen peroxide plasma sterilization. Zentralbl Steril. 2008;16:35–42. [Google Scholar]

230. Feldman LA, Hui HK. Compatibility of medical devices and materials with low-temperature hydrogen peroxide gas plasma. Med Dev Diag Indust. 1997;19:57–62. [Google Scholar]

231. Jacobs PT, Smith D. The new Sterrad 100S sterilization system: features and advantages. Zentralbl Steril. 1998;6:86–94. [Google Scholar]

232. Schembre DB. Infectious complications associated with gastrointestinal endoscopy. Gastrointest Endosc Clin North Am. 2000;10:215–232. [PubMed] [Google Scholar]

233. Weber DJ, Rutala WA. Lessons learned from outbreaks and pseudo-outbreaks associated with bronchoscopy. Infect Control Hosp Epidemiol. 2012;33:224–229. [PubMed] [Google Scholar]

234. Nelson DB, Jarvis WR, Rutala WA. Multi-society guideline for reprocessing flexible gastrointestinal endoscopes. Infect Control Hosp Epidemiol. 2003;24:532–537. [PubMed] [Google Scholar]

235. Society of Gastroenterology Nurses and Associates SGNA Standards of infection control in reprocessing of flexible gastrointestinal endoscopes. Gastroenterol Nurs. 2010;33:70–80. [PubMed] [Google Scholar]

236. Ofstead CL, Wetzler HP, Snyder AK. Endoscope reprocessing methods: a prospective study on the impact of human factors and automation. Gastroenterol Nurs. 2010;33:304–311. [PubMed] [Google Scholar]

237. Jackson FW, Ball MD. Correction of deficiencies in flexible fiberoptic sigmoidoscope cleaning and disinfection technique in family practice and internal medicine offices. Arch Fam Med. 1997;6:578–582. [PubMed] [Google Scholar]

238. Orsi GB, Filocamo A, Di Stefano L. Italian National Survey of Digestive Endoscopy Disinfection Procedures. Endoscopy. 1997;29:732–738. [PubMed] [Google Scholar]

239. Honeybourne D, Neumann CS. An audit of bronchoscopy practice in the United Kingdom: a survey of adherence to national guidelines. Thorax. 1997;52:709–713. [PMC free article] [PubMed] [Google Scholar]

240. Srinivasan A, Wolfenden LL, Song X. An outbreak of Pseudomonas aeruginosa infections associated with flexible bronchoscopes. N Engl J Med. 2003;348:221–227. [PubMed] [Google Scholar]

241. Cetse JC, Vanhems P. Outbreak of infection associated with bronchoscopes. N Engl J Med. 2003;348:2039–2040. [PubMed] [Google Scholar]

242. Rutala WA, Weber DJ. How to assess risk of disease transmission when there is a failure to follow recommended disinfection and sterilization principles. Infect Control Hosp Epidemiol. 2007;28:519–524. [PubMed] [Google Scholar]

243. Rutala WA, Weber DJ. FDA labeling requirements for disinfection of endoscopes: a counterpoint. Infect Control Hosp Epidemiol. 1995;16:231–235. [PubMed] [Google Scholar]

244. Kruse A, Rey JF. Guidelines on cleaning and disinfection in GI endoscopy: update 1999. The European Society of Gastrointestinal Endoscopy. Endoscopy. 2000;32:77–80. [PubMed] [Google Scholar]

245. British Society of Gastroenterology Cleaning and disinfection of equipment for gastrointestinal endoscopy. Report of a working party of the British Society of Gastroenterology Endoscope Committee. Gut. 1998;42:585–593. [PMC free article] [PubMed] [Google Scholar]

246. British Thoracic Society British Thoracic Society guidelines on diagnostic flexible bronchoscopy. Thorax. 2001;56(suppl 1):1–21. [PMC free article] [PubMed] [Google Scholar]

247. Occupational Safety and Health Administration Occupational exposure to bloodborne pathogens; final rule. Fed Register. 1991;56:64003–64182. [Google Scholar]

248. Occupational Safety and Health Administration . 1992. OSHA Instruction CPL 2-2.44C. Office of Health Compliance Assistance. Washington, DC, March 6. [Google Scholar]

249. Occupational Safety and Health Administration . 1997. OSHA Memorandum from Stephen Mallinger. EPA-Registered Disinfectants for HIV/HBV. Washington, DC; February 28. [Google Scholar]

250. Payan C, Cottin J, Lemarie C. Inactivation of hepatitis B virus in plasma by hospital in-use chemical disinfectants assessed by a modified HepG2 cell culture. J Hosp Infect. 2001;47:282–287. [PubMed] [Google Scholar]

251. Henderson DA. The looming threat of bioterrorism. Science. 1999;283:1279–1282. [PubMed] [Google Scholar]

252. Centers for Disease Control and Prevention Biological and chemical terrorism: strategic plan for preparedness and response. MMWR Recomm Rep. 2000;49(RR-4):1–14. [PubMed] [Google Scholar]

253. Rutala WA, Weber DJ. Infection control: the role of dis­infection and sterilization. J Hosp Infect. 1999;43(suppl):S43–S55. [PubMed] [Google Scholar]

254. Ryan SP, Calfee MW, Wood JP. Research to support the decontamination of surfaces and buildings contaminated with biothreat agents. In: Rutala WA, editor. Disinfection, Sterilization and Antisepsis: Principles, Practices, Current Issues, New Research, and New Technologies. Association for Professionals in Infection Control and Epidemiology; Washington, DC: 2010. pp. 260–306. [Google Scholar]

255. Rutala WA, Stiegel MM, Sarubbi FA. Susceptibility of antibiotic-susceptible and antibiotic-resistant hospital bacteria to disinfectants. Infect Control Hosp Epidemiol. 1997;18:417–421. [PubMed] [Google Scholar]

256. Weber DJ, Rutala WA. Use of germicides in the home and health care setting: is there a relationship between germicide use and antimicrobial resistance. Infect Control Hosp Epidemiol. 2006;27:1107–1119. [PubMed] [Google Scholar]

257. Rutala WA, Weber DJ. Guideline for disinfection and sterilization of prion-contaminated medical instruments. Infect Control Hosp Epidemiol. 2010;31:107–117. [PubMed] [Google Scholar]

258. Centers for Disease Control and Prevention Surveillance for Creutzfeldt-Jakob disease—United States. MMWR Morb Mortal Wkly Rep. 1996;45:665–668. [PubMed] [Google Scholar]

259. Belay ED, Schonberger LB, Brown P. Disinfection and sterilization of prion-contaminated medical instruments. Infect Control Hosp Epidemiol. 2010;31:1304–1306. [PubMed] [Google Scholar]

260. Rutala WA, Weber DJ. Disinfection and sterilization of prion-contaminated medical instruments: reply to Belay. Infect Control Hosp Epidemiol. 2010;31:1306–1307. [Google Scholar]

261. Secker TJ, Herve R, Keevil CW. Adsorption of prion and tissue proteins to surgical stainless steel surfaces and the efficacy of decontamination following dry and wet storage conditions. J Hosp Infect. 2011;78:251–255. [PubMed] [Google Scholar]

262. World Health Organization WHO Infection Control Guidelines for Transmissible Spongiform Encephalopathies. http://www.who.int/csr/resources/publications/bse/whocdscsraph2003.pdf Available at.

263. Rutala WA, Weber DJ. Creutzfeldt-Jakob disease: recommendations for disinfection and sterilization. Clin Infect Dis. 2001;32:1348–1356. [PubMed] [Google Scholar]

264. Taylor DM. Inactivation of prions by physical and chemical means. J Hosp Infect. 1999;43(suppl):S69–S76. [PubMed] [Google Scholar]

265. Otter JA. The role played by contaminated surfaces in the transmission of nosocomial pathogens. Infect Control Hosp Epidemiol. 2011;32:687–699. [PubMed] [Google Scholar]

266. Boyce JM. Environmental contamination makes an important contribution to hospital infection. J Hosp Infect. 2007;65:50–54. [PubMed] [Google Scholar]

267. Weber DJ, Rutala WA, Miller MB. Role of hospital surfaces in the transmission of emerging health care-associated pathogens: norovirus, Clostridium difficile, and Acinetobacter species. Am J Infect Control. 2010;38:S25–S33. [PubMed] [Google Scholar]

268. Rutala WA, Weber DJ. Are room decontamination units needed to prevent transmission of environmental pathogens? Infect Control Hosp Epidemiol. 2011;32:743–747. [PubMed] [Google Scholar]

269. Stiefel U, Cadnum JL, Eckstein BC. Contamination of hands with methicillin-resistant Staphylococcus aureus after contact with environmental surfaces and after contact with the skin of colonized patients. Infect Control Hosp Epidemiol. 2011;32:185–187. [PubMed] [Google Scholar]

270. Huang SS, Datta R, Platt R. Risk of acquiring antibiotic-resistant bacteria from prior room occupants. Arch Intern Med. 2006;166:1945–1951. [PubMed] [Google Scholar]

271. Shaughnessy MK, Micielli RL, DePestal DD. Evaluation of hospital room assignment and acquisition of Clostridium difficile infection. Infect Control Hosp Epidemiol. 2011;32:201–206. [PubMed] [Google Scholar]

272. Carling PC, Parry MF, Von Beheren SM, Healthcare Environmental Hygiene Study Group Identifying opportunities to enhance environmental cleaning in 23 acute care hospitals. Infect Control Hosp Epidemiol. 2008;29:1–7. [PubMed] [Google Scholar]

273. Carling PC, von Bheren S, Kim P. Intensive care unit environmental cleaning: an evaluation in sixteen hospitals using a novel assessment tool. J Hosp Infect. 2008;68:39–44. [PubMed] [Google Scholar]

274. Havill NL, Havill HL, Mangione E. Cleanliness of portable medical equipment disinfected by nursing staff. Am J Infect Control. 2011;39:602–604. [PubMed] [Google Scholar]

275. Hota B, Blom DW, Lyle EA. Intervention evaluation of environmental contamination by vancomycin-resistant enterococci: failure of personnel, product, or procedure? J Hosp Infect. 2009;71:123–131. [PubMed] [Google Scholar]

276. Goodman ER, Platt R, Bass R. Impact of an environmental cleaning intervention on the presence of methicillin-resistant Staphylococcus aureus and vancomycin-resistant enterococci on surfaces in intensive care unit rooms. Infect Control Hosp Epidemiol. 2008;29:593–599. [PMC free article] [PubMed] [Google Scholar]

277. Eckstein BC, Adams DA, Eckstein EC. Reduction of Clostridium difficile and vancomycin-resistant Enterococcus contamination of environmental surfaces after an intervention to improve cleaning methods. BMC Infect Dis. 2007;7:61. [PMC free article] [PubMed] [Google Scholar]

278. Rutala WA, Weber DJ. Sterilization, high-level disinfection, and environmental cleaning. Infect Dis Clin North Am. 2011;25:45–76. [PubMed] [Google Scholar]

279. Memarzadeh F, Olmsted RN, Bartley JM. Applications of ultraviolet germicidal irradiation disinfection in health care facilities: effective adjunct, but not stand-alone technology. Am J Infect Control. 2010;38:S13–S24. [PMC free article] [PubMed] [Google Scholar]

280. Rutala WA, Gergen MF, Weber DJ. Room decontamination by ultraviolet radiation. Infect Control Hosp Epidemiol. 2010;31:1025–1029. [PubMed] [Google Scholar]

281. Boyce JM, Havill NL, Moore BA. Terminal decontamination of patient rooms using an automated mobile UV light unit. Infect Control Hosp Epidemiol. 2011;32:743–747. [PubMed] [Google Scholar]

282. Nerandzic MM, Cadnum JL, Pultz MJ. Evaluation of an automated ultraviolet radiation device for decon­tamination of Clostridium difficile and other healthcare-associated pathogens in hospital rooms. BMC Infect Dis. 2010;10:197. [PMC free article] [PubMed] [Google Scholar]

283. Boyce JM, Havill NL, Otter JA. Impact of hydrogen peroxide vapor room decontamination on Clostridium difficile environmental contamination and transmission in a healthcare setting. Infect Control Hosp Epidemiol. 2008;29:723–729. [PubMed] [Google Scholar]

284. French GL, Otter JA, Shannon KP. Tackling contamination of the hospital environment by methicillin-resistant Staphylococcus aureus (MRSA): a comparison between conventional terminal cleaning and hydrogen peroxide vapour decontamination. J Hosp Infect. 2004;57:31–37. [PubMed] [Google Scholar]

285. Bartels MD, Kristofferson K, Slotsbjerg T. Environmental methicillin-resistant Staphylococcus aureus (MRSA) disinfection using dry-mist-generated hydrogen peroxide. J Hosp Infect. 2008;70:35–41. [PubMed] [Google Scholar]

286. Hall L, Otter JA, Chewins J. Use of hydrogen peroxide vapor for deactivation of Mycobacterium tuberculosis in a biological safety cabinet and a room. J Clin Microbiol. 2007;45:810–815. [PMC free article] [PubMed] [Google Scholar]

287. Hardy KJ, Gossain S, Henderson N. Rapid recontamination with MRSA of the environment of an intensive care unit after decontamination with hydrogen peroxide vapour. J Hosp Infect. 2007;66:360–368. [PubMed] [Google Scholar]

288. Johnston MD, Lawson S, Otter JA. Evaluation of hydrogen peroxide vapour as a method for the decontamination of surfaces contaminated with Clostridium botulinum spores. J Microbiol Methods. 2005;60:403–411. [PubMed] [Google Scholar]

289. Heckert RA, Best M, Jordan LT. Efficacy of vaporized hydrogen peroxide against exotic animal viruses. Appl Environ Microbiol. 1997;63:3916–3918. [PMC free article] [PubMed] [Google Scholar]

290. Klapes NA, Vesley D. Vapor-phase hydrogen peroxide as a surface decontaminant and sterilant. Appl Environ Microbiol. 1990;56:503–506. [PMC free article] [PubMed] [Google Scholar]

291. Bates CJ, Pearse R. Use of hydrogen peroxide vapour for environmental control during a Serratia outbreak in a neonatal intensive care unit. J Hosp Infect. 2005;61:364–366. [PubMed] [Google Scholar]

292. Shapey S, Machin K, Levi K. Activity of a dry mist hydrogen peroxide system against environmental Clostridium difficile contamination in elderly care wards. J Hosp Infect. 2008;70:136–141. [PubMed] [Google Scholar]

293. Rutala WA, Odette RL, Samsa GP. Management of infectious waste by United States hospitals. JAMA. 1989;262:1635–1640. [PubMed] [Google Scholar]

294. Rutala WA, Sarubbi FA. Management of infectious waste from hospitals. Infect Control. 1983;4:198–204. [PubMed] [Google Scholar]

295. Agency for Toxic Substances and Disease Registry . U.S. Department of Health and Human Services; Washington, DC: 1990. The Public Health Implications of Medical Waste: A Report to Congress. [Google Scholar]

296. Environmental Protection Agency . U.S. Environmental Protection Agency; Washington, DC: 1986. EPA Guide for Infectious Waste Management. [Google Scholar]

297. Office of Technology Assessment (OTA-0-459 . Government Printing Office; Washington, DC: 1990. Finding the Rx for Managing Medical Wastes. [Google Scholar]

298. Environmental Protection Agency Standards for the tracking and management of medical waste; interim final rule and request for comments. Fed Register. 1989;54:12326–12395. [Google Scholar]

299. Rutala WA, Weber DJ. Infectious waste: mismatch between science and policy. N Engl J Med. 1991;325:578–582. [PubMed] [Google Scholar]

300. Environmental Protection Agency Hospital/Medical/Infectious Waste Incinerators: Summary of requirements for revised or new section 111(d)/129 State plans following amendments to the emission guidelines. 2010. http://www.epa.gov/ttn/atw/129/hmiwi/rihmiwi.html Available at.

301. Rutala WA, Mayhall CG, Society for Hospital Epidemiology of America SHEA position paper: Medical waste. Infect Control Hosp Epidemiol. 1992;13:38–48. [PubMed] [Google Scholar]

302. U.S. Department of Transportation Infectious substances: final rule. Fed Register. 1995;60:48779–48787. [Google Scholar]

303. Rutala WA. Selection and use of disinfectants in healthcare. In: Mayhall CG, editor. Hospital Epidemiology and Infection Control. 2nd ed. Lippincott Williams & Wilkins; Philadelphia: 1999. pp. 1161–1187. [Google Scholar]

304. Rutala WA, Weber DJ. Sterilization and disinfection. In: Jarvis WR, editor. Bennett & Brachman's Hospital Infections. 5th ed. Wolters Kluwer/Lippincott Williams & Wilkins; Philadelphia: 2007. pp. 303–318. [Google Scholar]


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Methods of Sterilization and Disinfection

STERILIZATIONDISINFECTION
Critical Items (will enter tissue or vascular system or blood will flow through them)High-Level (semicritical items [except dental] will come in contact with mucous membrane or nonintact skin)Intermediate-Level (some semicritical items1 and noncritical items)Low-Level (noncritical items; will come in contact with intact skin)
ObjectProcedureExposure TimeProcedure (exposure time 12-45 min at ≥20° C2, 3)Procedure (exposure time ≥1 min9)Procedure (exposure time ≥1 min9)
Smooth, hard surface1, 4AMRD
AMREL5L
CMRFMM
D10 hr at 20-25° CGNN
F6 hrHPO
G12 min at 50°-56° CI6QP
JQ
H3-8 hrK
Rubber tubing and catheters3, 4AMRD
BMRE
CMRF
D10 hr at 20°-25° CG
F6 hrH
G12 min at 50°-56° CI6
H3-8 hrJ
K
Polyethylene tubing and catheters3, 4, 7AMRD
BMRE
CMRF
D10 hr at 20°-25° CG
F6 hrH
G12 min at 50°-56° CI6
H3-8 hrJ
K
Lensed instruments4AMRD
BMRE
CMRF
D10 hr at 20°-25° CG
F6 hrH
G12 min at 50°-56° CJ
H3-8 hrK
Thermometers (oral and rectal)8P8
Hinged instruments4AMRD
BMRE
CMRF
D10 hr at 20°-25° CG
F6 hrH
G12 min at 50°-56° CI6
H3-8 hrJ
K

Modified from the works of Rutala and Simmons and their colleagues.9, 10, 13, 16, 18, 19, 303