A nurse in the emergency department is caring for a client who has bleeding esophageal varices

1. Nowak DD, Lee JK, Gelb DE, Poelstra KA, Ludwig SC. Central cord syndrome. J Am Acad Orthop Surg. 2009;17(12):756–765. doi: 10.5435/00124635-200912000-00004. [PubMed] [CrossRef] [Google Scholar]

2. Barletta J, Bruno J, Buckley M, Cook D. Stress ulcer prophylaxis. Crit Care Med. 2016;44(7):1395–1405. doi: 10.1097/CCM.0000000000001872. [PubMed] [CrossRef] [Google Scholar]

3. Mermel LA, Allon M, Bouza E, et al. Clinical practice guidelines for the diagnosis and management of intravascular catheter-related infection: 2009 update by the Infectious Diseases Society of America. Clin Infect Dis. 2009;49(1):1–45. doi: 10.1086/599376. [PMC free article] [PubMed] [CrossRef] [Google Scholar]

4. Rahimi RS, Singal AG, Cuthbert JA, Rockey DC. Lactulose vs polyethylene glycol 3350—electrolyte solution for treatment of overt hepatic encephalopathy: the HELP randomized clinical trial. JAMA Intern Med. 2014;174(11):1727–1733. doi: 10.1001/jamainternmed.2014.4746. [PMC free article] [PubMed] [CrossRef] [Google Scholar]

5. Hocker SE, Tian L, Li G, Steckelberg JM, Mandrekar JN, Rabinstein AA. Indicators of central fever in the neurologic intensive care unit. JAMA Neurol. 2013;70(12):1499–1504. [PubMed] [Google Scholar]

6. O'gara PT, Kushner FG, Ascheim DD, et al. 2013 ACCF/AHA guideline for the management of ST-elevation myocardial infarction: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol. 2013;61(4):e78–140. doi: 10.1016/j.jacc.2012.11.019. [PubMed] [CrossRef] [Google Scholar]

7. Ranieri VM, Rubenfeld GD, Thompson BT, et al. Acute respiratory distress syndrome: the Berlin definition. JAMA. 2012;307(23):2526–2533. [PubMed] [Google Scholar]

8. Wiemels J, Wrensch M, Claus EB. Epidemiology and etiology of meningioma. J Neuro-Oncol. 2010;99(3):307–314. doi: 10.1007/s11060-010-0386-3. [PMC free article] [PubMed] [CrossRef] [Google Scholar]

9. Barnett HJ, Taylor DW, Eliasziw M, et al. Benefit of carotid endarterectomy in patients with symptomatic moderate or severe stenosis. North American Symptomatic Carotid Endarterectomy Trial Collaborators. N Engl J Med. 1998;339(20):1415–1425. doi: 10.1056/NEJM199811123392002. [PubMed] [CrossRef] [Google Scholar]

10. Jaff MR, Mcmurtry MS, Archer SL, et al. Management of massive and submassive pulmonary embolism, iliofemoral deep vein thrombosis, and chronic thromboembolic pulmonary hypertension: a scientific statement from the American Heart Association. Circulation. 2011;123(16):1788–1830. doi: 10.1161/CIR.0b013e318214914f. [PubMed] [CrossRef] [Google Scholar]

11. Denis F. The three column spine and its significance in the classification of acute thoracolumbar spinal injuries. Spine. 1983;8(8):817–831. doi: 10.1097/00007632-198311000-00003. [PubMed] [CrossRef] [Google Scholar]

12. Dalmau J, Lancaster E, Martinez-hernandez E, Rosenfeld MR, Balice-gordon R. Clinical experience and laboratory investigations in patients with anti-NMDAR encephalitis. Lancet Neurol. 2011;10(1):63–74. doi: 10.1016/S1474-4422(10)70253-2. [PMC free article] [PubMed] [CrossRef] [Google Scholar]

13. Marko NF, Gonugunta VA, Hamrahian AH, Usmani A, Mayberg MR, Weil RJ. Use of morning serum cortisol level after transsphenoidal resection of pituitary adenoma to predict the need for long-term glucocorticoid supplementation. J Neurosurg. 2009;111(3):540–544. doi: 10.3171/2008.12.JNS081265. [PubMed] [CrossRef] [Google Scholar]

14. Freeman WD, Sen S, Roy TK, Wijdicks EF. Cluster breathing associated with bihemispheric infarction and sparing of the brainstem. Arch Neurol. 2006;63(10):1487–1490. doi: 10.1001/archneur.63.10.1487. [PubMed] [CrossRef] [Google Scholar]

15. Seneviratne J, Mandrekar J, Wijdicks EF, Rabinstein AA. Noninvasive ventilation in myasthenic crisis. Arch Neurol. 2008;65(1):54–58. doi: 10.1001/archneurol.2007.1. [PubMed] [CrossRef] [Google Scholar]

16. Polson J, Lee WM. AASLD position paper: the management of acute liver failure. Hepatology. 2005;41(5):1179–1197. doi: 10.1002/hep.20703. [PubMed] [CrossRef] [Google Scholar]

17. Kim HS. Endoscopic management of mallory-weiss tearing. Clin Endosc. 2015;48(2):102–105. doi: 10.5946/ce.2015.48.2.102. [PMC free article] [PubMed] [CrossRef] [Google Scholar]

18. Washington C, Carmichael JC. Management of ischemic colitis. Clin Colon Rectal Surg. 2012;25(4):228–235. doi: 10.1055/s-0032-1329534. [PMC free article] [PubMed] [CrossRef] [Google Scholar]

19. Belfort MA, Anthony J, Saade GR, Allen JC. A comparison of magnesium sulfate and nimodipine for the prevention of eclampsia. N Engl J Med. 2003;348(4):304–311. doi: 10.1056/NEJMoa021180. [PubMed] [CrossRef] [Google Scholar]

20. Scheller C, Wienke A, Tatagiba M, et al. Prophylactic nimodipine treatment for cochlear and facial nerve preservation after vestibular schwannoma surgery: a randomized multicenter Phase III trial. J Neurosurg. 2016;124(3):657–664. doi: 10.3171/2015.1.JNS142001. [PubMed] [CrossRef] [Google Scholar]

21. Diehl JL, Peigne V, Guérot E, Faisy C, Lecourt L, Mercat A. Helium in the adult critical care setting. Ann Intensive Care. 2011;1(1):24. doi: 10.1186/2110-5820-1-24. [PMC free article] [PubMed] [CrossRef] [Google Scholar]

22. Robinson N, Clancy M. In patients with head injury undergoing rapid sequence intubation, does pretreatment with intravenous lignocaine/lidocaine lead to an improved neurological outcome? A review of the literature. Emerg Med J. 2001;18(6):453–457. doi: 10.1136/emj.18.6.453. [PMC free article] [PubMed] [CrossRef] [Google Scholar]

23. Mandybur TI. Intracranial hemorrhage caused by metastatic tumors. Neurology. 1977;27(7):650–655. doi: 10.1212/WNL.27.7.650. [PubMed] [CrossRef] [Google Scholar]

24. Cui Z, Wang B, Zhong Z, et al. Impact of antibiotic- and silver-impregnated external ventricular drains on the risk of infections: a systematic review and meta-analysis. Am J Infect Control. 2015;43(7):e23–e32. doi: 10.1016/j.ajic.2015.03.015. [PubMed] [CrossRef] [Google Scholar]

25. Armin SS, Colohan AR, Zhang JH. Vasospasm in traumatic brain injury. Acta Neurochir Suppl. 2008;104(13):421–425. doi: 10.1007/978-3-211-75718-5_88. [PMC free article] [PubMed] [CrossRef] [Google Scholar]

26. Rutten-jacobs LC, Traylor M, Adib-samii P, et al. Common NOTCH3 variants and cerebral small-vessel disease. Stroke. 2015;46(6):1482–1487. doi: 10.1161/STROKEAHA.114.008540. [PMC free article] [PubMed] [CrossRef] [Google Scholar]

27. Miller RG, Mitchell JD, Moore DH. Riluzole for amyotrophic lateral sclerosis (ALS)/motor neuron disease (MND) Cochrane Database Syst Rev. 2012;3:CD001447. [PMC free article] [PubMed] [Google Scholar]

28. Haapaniemi E, Strbian D, Rossi C, et al. The CAVE score for predicting late seizures after intracerebral hemorrhage. Stroke. 2014;45(7):1971–1976. doi: 10.1161/STROKEAHA.114.004686. [PubMed] [CrossRef] [Google Scholar]

29. Young D, Harrison DA, Cuthbertson BH, Rowan K. Effect of early vs late tracheostomy placement on survival in patients receiving mechanical ventilation: the TracMan randomized trial. JAMA. 2013;309(20):2121–2129. doi: 10.1001/jama.2013.5154. [PubMed] [CrossRef] [Google Scholar]

30. Andriolo BN, Andriolo RB, Saconato H, Atallah ÁN, Valente O. Early versus late tracheostomy for critically ill patients. Cochrane Database Syst Rev. 2015;1:CD007271. [PMC free article] [PubMed] [Google Scholar]

31. Yanaka K, Matsumaru Y, Nose T. Management of spontaneous cerebellar hematomas: a prospective treatment protocol. Neurosurgery. 2002;51(2):524–525. doi: 10.1227/00006123-200208000-00051. [PubMed] [CrossRef] [Google Scholar]

32. Pickard JD, Czosnyka M. Management of raised intracranial pressure. J Neurol Neurosurg Psychiatry. 1993;56(8):845–858. doi: 10.1136/jnnp.56.8.845. [PMC free article] [PubMed] [CrossRef] [Google Scholar]

33. Tan IL, Mcarthur JC, Venkatesan A, Nath A. Atypical manifestations and poor outcome of herpes simplex encephalitis in the immunocompromised. Neurology. 2012;79(21):2125–2132. doi: 10.1212/WNL.0b013e3182752ceb. [PMC free article] [PubMed] [CrossRef] [Google Scholar]

34. Weinstein GM, Arkun K, Kryzanski J, Lanfranchi M, Gupta GK, Bedi H. Spinal intradural extramedullary ependymoma with astrocytoma component: a case report and review of the literature. Case Rep Pathol. 2016;2016:3534791. [PMC free article] [PubMed] [Google Scholar]

35. Kalil AC, Metersky ML, Klompas M, et al. Management of Adults With Hospital-acquired and Ventilator-associated Pneumonia: 2016 Clinical practice guidelines by the Infectious Diseases Society of America and the American Thoracic Society. Clin Infect Dis. 2016;63(5):e61–e111. [PMC free article] [PubMed]

36. Roberts I, Yates D, Sandercock P, et al. Effect of intravenous corticosteroids on death within 14 days in 10008 adults with clinically significant head injury (MRC CRASH trial): randomised placebo-controlled trial. Lancet. 2004;364(9442):1321–1328. doi: 10.1016/S0140-6736(04)17188-2. [PubMed] [CrossRef] [Google Scholar]

37. Wright DW, Yeatts SD, Silbergleit R, et al. Very early administration of progesterone for acute traumatic brain injury. N Engl J Med. 2014;371(26):2457–2466. doi: 10.1056/NEJMoa1404304. [PMC free article] [PubMed] [CrossRef] [Google Scholar]

38. Turner DA, Cheifetz IM. Extracorporeal membrane oxygenation for adult respiratory failure. Respir Care. 2013;58(6):1038–1052. doi: 10.4187/respcare.02255. [PubMed] [CrossRef] [Google Scholar]

39. Dubuisson AS, Beckers A, Stevenaert A. Classical pituitary tumour apoplexy: clinical features, management and outcomes in a series of 24 patients. Clin Neurol Neurosurg. 2007;109(1):63–70. doi: 10.1016/j.clineuro.2006.01.006. [PubMed] [CrossRef] [Google Scholar]

40. Rabinstein AA, Tisch SH, Mcclelland RL, Wijdicks EF. Cause is the main predictor of outcome in patients with pontine hemorrhage. Cerebrovasc Dis. 2004;17(1):66–71. doi: 10.1159/000073900. [PubMed] [CrossRef] [Google Scholar]

41. Lacombe P, Lagrange C, Beauchet A, El Hajjam M, Chinet T, Pelage JP. Diffuse pulmonary arteriovenous malformations in hereditary hemorrhagic telangiectasia: long-term results of embolization according to the extent of lung involvement. Chest. 2009;135(4):1031–1037. doi: 10.1378/chest.08-1794. [PubMed] [CrossRef] [Google Scholar]

42. Bar B, Mackenzie L, Hurst RW, et al. Hyperacute vasospasm after aneurysmal subarachnoid hemorrhage. Neurocrit Care. 2016;24(2):180–188. doi: 10.1007/s12028-015-0177-y. [PubMed] [CrossRef] [Google Scholar]

43. Behrns KE, Ashley SW, Hunter JG, Carr-locke D. Early ERCP for gallstone pancreatitis: for whom and when? J Gastrointest Surg. 2008;12(4):629–633. doi: 10.1007/s11605-007-0289-6. [PubMed] [CrossRef] [Google Scholar]

44. Seamon MJ, Haut ER, Van Arendonk K, et al. An evidence-based approach to patient selection for emergency department thoracotomy: a practice management guideline from the Eastern Association for the Surgery of Trauma. J Trauma Acute Care Surg. 2015;79(1):159–173. doi: 10.1097/TA.0000000000000648. [PubMed] [CrossRef] [Google Scholar]

45. Lomas DJ, Padley SG, Flower CD. The sonographic appearances of pleural fluid. Br J Radiol. 1993;66(787):619–624. doi: 10.1259/0007-1285-66-787-619. [PubMed] [CrossRef] [Google Scholar]

46. Sharshar T, Chevret S, Bourdain F, Raphaël JC. Early predictors of mechanical ventilation in Guillain-Barré syndrome. Crit Care Med. 2003;31(1):278–283. doi: 10.1097/00003246-200301000-00044. [PubMed] [CrossRef] [Google Scholar]

47. Roth C, Ferbert A, Deinsberger W, et al. Does prone positioning increase intracranial pressure? A retrospective analysis of patients with acute brain injury and acute respiratory failure. Neurocrit Care. 2014;21(2):186–191. doi: 10.1007/s12028-014-0004-x. [PubMed] [CrossRef] [Google Scholar]

48. Naff N, Williams MA, Keyl PM, et al. Low-dose recombinant tissue-type plasminogen activator enhances clot resolution in brain hemorrhage: the intraventricular hemorrhage thrombolysis trial. Stroke. 2011;42(11):3009–3016. doi: 10.1161/STROKEAHA.110.610949. [PMC free article] [PubMed] [CrossRef] [Google Scholar]

49. Hanley D. Clot lysis: evaluating accelerated resolution of intraventricular hemorrhage phase III (CLEAR-III). ClinicalTrials.gov identifier. NCT00784134.

50. Frontera JA, Claassen J, Schmidt JM, et al. Prediction of symptomatic vasospasm after subarachnoid hemorrhage: the modified fisher scale. Neurosurgery. 2006;59(1):21–27. doi: 10.1227/01.NEU.0000218821.34014.1B. [PubMed] [CrossRef] [Google Scholar]

51. Brouwer MC, Tunkel AR, Mckhann GM, Van de Beek D. Brain abscess. N Engl J Med. 2014;371(5):447–456. doi: 10.1056/NEJMra1301635. [PubMed] [CrossRef] [Google Scholar]

52. Fuller BM, Mohr NM, Miller CN, et al. Mechanical ventilation and ARDS in the ED: a multicenter, observational, prospective, cross-sectional study. Chest. 2015;148(2):365–374. doi: 10.1378/chest.14-2476. [PMC free article] [PubMed] [CrossRef] [Google Scholar]


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AmpicillinR > 16
CeftriaxoneS < 1
CefepimeS < 4
CefoxitinS < 8
Piperacillin/tazobactamS < 16